Ovulation Monitoring

Many women wish to try a monitored cycle to conceive prior to considering more complicated treatments such as IVF. If you are ovulating regularly, then often a good explanation by Dr Jessup about the fertile times of your cycle and the best likely days for sex will be all that is required. For women with irregular cycles, however, the timing method does not work so well. If is important to see the doctor before undertaking monitored cycles to see if there is a diagnosable reason which explains the cycle irregularity, as simple treatments may sometimes correct the process.

For women that do require ovulation monitoring Shire IVF helps by tracking your hormone cycle using a combination of blood tests and ultrasound scans to predict when ovulation is going to take place. This information can then be used to time sex or alternatively a “ trigger” injection may be used to accurately pinpoint the timing of the release of the egg to make the best timing of intercourse even more precise

OVULATION INDUCTION

If your cycle is very long or even absent in some case, you may benefit from ovulation induction. This process involves taking medication to induce ovulation by encouraging eggs to develop in the ovaries and be released, increasing the chance of conception through timed intercourse or intrauterine insemination At Shire IVF, Dr Jessup uses one of three different types to medication to help the ovaries release an egg in a normal timeframe.

CLOMIPHENE CITRATE
(Clomid)

This oral medication used to induce ovulation in women who do not ovulate on their own by encouraging the body to produce more follicle stimulate hormone (FSH). Most commonly used if a woman has irregular or long menstrual cycles. Clomiphene citrate is the most commonly used pharmacologic agent to induce ovulation in women with polycystic ovaries and is taken as 1-2 oral tablets daily from the second day of your period for five days.

AROMATASE INHIBITORS
(Letrozole)

Some women whose ovaries do not respond to Clomiphene citrate, benefit from using a different oral tablet, again taking 1-2 tablets daily for five days from the second day of your Period Aromatase inhibitors are a class of drugs that block estrogen biosynthesis, thereby reducing negative estrogenic feedback at the pituitary. Letrozole is at least as effective as clomiphene for inducing ovulation and achieving pregnancy in patients with polycystic ovarian syndrome. Potential advantages of letrozole include reduced multiple pregnancies, absence of antiestrogenic adverse effects, and the subsequent need for less intensive monitoring.

FOLLICLE STIMULATING HORMONE
(FHS - eg Purgeon/Gonal F)

These medicines fall under a group called Gonadotrphins and need to be given as a daily injection under the skin.This is the same type of medication used in IVF cycles, but given at a much lower dose. Hormone injections of FSH can be used to stimulate the number of follicles that develop in the ovary and therefore the number of eggs that are ovulated during a cycle. Another hormone hCG may be used in injection form to trigger ovulation once the follicles have developed.

Monitoring of an Ovulation Induction cycle is essential no matter which medication you are using to ensure that only one or two eggs develop . If too many eggs develop at once this may lead to the risk of multiple pregnancies which is not safe or desirable. At Shire IVF by undertaking a combination of blood tests and ultrasounds you’ll receive a more accurate and comprehensive overview of your cycle and general fertility in a safe, controlled manner.